HealthBreaking
Novartis drug pelacarsen does not reduce heart attacks or strokes in clinical trial
By Mantle News
Coverage spectrum
Covered by 3 outlets, all left-leaning.
3 articles in total. The spectrum counts each outlet once and leaves opinion out. How we measure bias
CNN, NBC News and NPR report that pelacarsen, an experimental drug from Novartis designed to lower lipoprotein(a), a fat-carrying protein in the blood, did not reduce heart attacks, strokes or cardiovascular deaths in the Horizon clinical trial. The results were presented Saturday at the American Heart Association’s annual meeting. The outlets say the trial enrolled nearly 800 sites and that the drug also did not reduce procedures to open blocked arteries. Before the results, researchers had expected a positive outcome, and NBC News quotes them calling the result a massive blow to preventive cardiology.
Headline and summary written by Mantle’s AI from the coverage below, under published rules. Editors read every story. How this works
What happened
Key points
Each point shows who reports it, from Far Left to Far Right.
The pelacarsen trial (Horizon) did not show a reduction in heart attacks or strokes.
One side only: the leftReported byLeft3See the outletsHide the outlets
- Left
- CNN, NBC News, NPR
The results were presented Saturday at the American Heart Association’s annual meeting.
One side only: the leftReported byLeft2See the outletsHide the outlets
- Left
- CNN, NBC News
The drug is designed to lower lipoprotein(a), a form of cholesterol that builds up in arteries.
One side only: the leftReported byLeft2See the outletsHide the outlets
- Left
- CNN, NBC News
The trial involved nearly 800 sites, and researchers said the result was a massive blow to preventive cardiology.
One outletNBC News· Left
How each side tells it
Compare views
CNN, NBC News and NPR all report that pelacarsen did not reduce heart attacks or strokes in a large trial. As only left-side outlets appear in this sample, their coverage presents the result mainly as a surprise and a setback, with CNN and NBC using more dramatic language.
the left
3 outlets
All three headlines present the trial as a failure or setback, with CNN using the strongest wording (“flops”) and NPR the most neutral (“fails unexpectedly”).
A promising drug for an inherited heart risk Loaded verb“flops”The verb “flops” adds a judgement of failure and ridicule beyond the trial result itself.More neutral: does not succeedDisagree with this highlight?, stunning doctors
CNNLeftAll left-leaning headlines the center
No coverage yet
No center outlet that Mantle follows has covered this story yet. That absence is part of the picture.
the right
No coverage yet
No right-leaning outlet that Mantle follows has covered this story yet. That absence is part of the picture.
The words they chose
Language to notice
Words that carry a judgement beyond the facts. Tap a highlighted word anywhere on the page to see why.
Left1
flops
Center
Has not covered this story.
Right
Has not covered this story.
In the outlets’ own words
Loaded verb
flopsMore neutral: does not succeed
The verb “flops” adds a judgement of failure and ridicule beyond the trial result itself.
A promising drug for an inherited heart risk flops, stunning doctors
Used byCNN (Left)
Words quoted from someone else (1)Hide the quoted words
Loaded words that outlets reported someone else saying. They show what was said, not how the outlet chose to say it.
Sensational language
Quotedmassive blowMore neutral: a significant setback
The phrase is a dramatic characterization of the trial result, even though it is attributed to researchers.
…people who have high levels of lipoprotein(a) stunned researchers, who called it a massive blow to preventive cardiology.
Quoted byNBC News (Left)
These are unnamed researchers’s words. The outlets are reporting them.
See for yourself
Side by side
What each side leads with and what it leaves out. Open a side to read its headlines.
From the left
3 outletsLeads with
- the drug’s failure on its key measure
- surprise among doctors and researchers
- the hopes placed in the drug
See the 3 headlines from the leftHide the headlines
- CNNLeft
A promising drug for an inherited heart risk Loaded verb“flops”The verb “flops” adds a judgement of failure and ridicule beyond the trial result itself.More neutral: does not succeedDisagree with this highlight?, stunning doctors
In the course of scientific discovery, there are triumphant moments when researchers present their findings to a rapt audience that jumps to its feet for a standing ovation. …
- NBC NewsLeft
The ‘slam dunk’ that wasn’t: Promising cholesterol drug fails to prevent heart attacks or stroke
An experimental drug that held great promise in driving down a dangerous form of cholesterol didn’t show any measurable impact on heart attack or stroke in a clinical trial.
- NPRLeft
A promising new medicine against heart disease fails unexpectedly
Doctors expected an experimental drug that lowers a common risk factor for heart attacks would save patients' lives. The medicine made no difference.
From the center
0 outletsNo center outlet that Mantle follows has covered this story yet. That absence is part of the picture.
From the right
0 outletsNo right-leaning outlet that Mantle follows has covered this story yet. That absence is part of the picture.
The stories you read build My Mix, a private picture of which sides cover the stories you choose, kept on this device. What is My Mix?
The left is Far Left and Left together. The right is Right and Far Right together. Every outlet keeps its own five-point rating.
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